Biblioteca Hospital 12 de Octubre
Serna Torroba, Javier de la

Complex, Not Monosomal, Karyotype Is the Cytogenetic Marker of Poorest Prognosis in Patients With Primary Myelodysplastic Syndrome. [artículo] - Journal of Clinical Oncology, 2013 - 31(7):916-22.

Formato Vancouver:
Valcárcel D, Ademà V, Solé F, Ortega M, Nomdedeu B, Sanz G et al. Complex, not monosomal, karyotype is the cytogenetic marker of poorest prognosis in patients with primary myelodysplastic syndrome. J Clin Oncol. 2013 Mar 1;31(7):916-22.

PMID: 23319689

Contiene 17 referencias

Purpose Complex karyotype (CK) is the poorest risk factor in patients with myelodysplastic syndrome (MDS). It has recently been reported that monosomal karyotype (MK) worsens the prognosis of patients with CK. Patients and Methods We analyzed 1,054 adult patients with MDS with an abnormal karyotype from the Spanish Registry of MDS. The aim of the study was to describe the incidence, characteristics, and prognosis of MK; the main end points were overall survival (OS) and leukemia-free survival.

Con tecnología Koha