La utilidad de la nitroglicerina tópica al 0,2% en la condrodermatitis nodular del hélix. [artículo]
Por: Gutiérrez García-Rodrigo, Carlota [Dermatología Médico-Quirúrgica y Venereología] | Vanaclocha Sebastián, Francisco [Dermatología Médico Quirúrgica y Venereología].
Colaborador(es): Servicio de Dermatología Médico-Quirúrgica y Venereología.
Tipo de material: ArtículoEditor: Actas dermo-sifiliográficas, 2015Descripción: 106(7):555-61.Recursos en línea: Solicitar documento Resumen: Background and objective: Chondrodermatitis nodularis helicis (CNH) is a painful idiopathic degenerative condition involving the skin and cartilage of the helix or antihelix of the ear. Topical nitroglycerin 2% is a relatively recent treatment option for CNH that has produced good results, although with adverse effects (17% of cases). The use of a lower concentration would probably achieve similar results with fewer adverse effects. The aim of this study was to evaluate the effectiveness and safety of topical nitroglycerin 0.2% in the treatment of CNH. Material and methods: We performed a retrospective observational study of patients treated in 2 Spanish hospitals between 2012 and 2014. The effectiveness of treatment was determined by clinical photography and assessment of symptoms using a verbal numerical rating scale. Results: Of the 29 patients treated, 93% showed clinical improvement. In the group of responders, mean treatment duration was 1.8 months and mean follow-up was 5.9 months. Overall tolerance was good in all cases. Conclusion: Topical nitroglycerin 0.2% is an effective and well-tolerated conservative treatment option that improves the appearance of lesions and provides symptomatic relief in the majority of patients with CNH.Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
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Artículo | PC17441 (Navegar estantería) | Disponible |
Formato Vancouver:
Sanz Motilva V, Martorell Calatayud A, Gutiérrez García-Rodrigo C, Hueso Gabriel L, García Melgares ML, Pelufo Enguix C et al. La utilidad de la nitroglicerina tópica al 0,2% en la condrodermatitis nodular del hélix. Actas Dermosifiliogr. 2015 Sep;106(7):555-61.
PMID: 26001657
Contiene 15 referencias
Background and objective: Chondrodermatitis nodularis helicis (CNH) is a painful idiopathic degenerative condition involving the skin and cartilage of the helix or antihelix of the ear. Topical nitroglycerin 2% is a relatively recent treatment option for CNH that has produced good results, although with adverse effects (17% of cases). The use of a lower concentration would probably achieve similar results with fewer adverse effects. The aim of this study was to evaluate the effectiveness and safety of topical nitroglycerin 0.2% in the treatment of CNH.
Material and methods: We performed a retrospective observational study of patients treated in 2 Spanish hospitals between 2012 and 2014. The effectiveness of treatment was determined by clinical photography and assessment of symptoms using a verbal numerical rating scale.
Results: Of the 29 patients treated, 93% showed clinical improvement. In the group of responders, mean treatment duration was 1.8 months and mean follow-up was 5.9 months. Overall tolerance was good in all cases.
Conclusion: Topical nitroglycerin 0.2% is an effective and well-tolerated conservative treatment option that improves the appearance of lesions and provides symptomatic relief in the majority of patients with CNH.
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