000 01584na a2200193 4500
003 PC10456
005 20180417105938.0
008 130622s2001
040 _cH12O
100 _aLeón Sanz, Miguel
_91057
_eEndocrinología y Nutrición
245 0 0 _aManual de recomendaciones nutricionales al alta hospitalaria
_h[libro]
260 _aBarcelona:
_bYou&Us,
_c2001.
300 _a309 p. ;
_c30 cm.
500 _aFormato Vancouver: León Sanz M, Celaya Pérez, S, editores. Manual de recomendaciones nutricionales al alta hospitalaria. barcelona. You&Us; 2001.
520 _aBackground: Some epidemiological, genetic, and experimental data suggest a possible role of vitamin D in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis. Data on the possible contribution of several single nucleotide polymorphisms (SNP) in the vitamin D receptor (VDR) gene to the risk for MS are controversial. Several studies suggested an interaction between some SNPs in the VDR gene and HLADRB1*1501 in the risk for MS. Objectives: The aim of this study was to investigate a possible influence of the SNPs rs2228570 and rs731236 in the VDR gene in the risk for MS. A secondary objective was to address the possible interactions between VDR genes and HLADRB1*1501. Methods: We analyzed the allelic and genotype frequency of VDR rs2228570, rs731236, and HLADRB1*1501 (rs3135388) in 303 patients with
710 _9292
_aServicio de Endocrinología y Nutrición
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc10456.pdf
_ySólo Portada
942 _2ddc
_cLIB
_n0
999 _c10456
_d10456