000			nab a22 7a 4500
999			_c16636 _d16636
003			PC16636
005			20211102125603.0
008			211102b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_91167 _aMedina Benítez, Enrique _ePediatría
245	0	4	_aThe complete picture of changing pediatric inflammatory bowel disease incidence in Spain in 25 years (1985-2009): the EXPERIENCE registry. _h[artículo]
260			_bJournal of Crohn's & colitis, _c2014
300			_a8(8):763-9.
500			_aFormato Vancouver: Martín de Carpi J, Rodríguez A, Ramos E, Jiménez S, Martínez Gómez MJ, Medina E et al; SPIRIT-IBD Working Group of SEGHNP (Sociedad Española de Gastroenterología Hepatología Nutrición Pediátrica). The complete picture of changing pediatric inflammatory bowel disease incidence in Spain in 25 years (1985-2009): the EXPERIENCE registry. J Crohns Colitis. 2014 Aug;8(8):763-9.
501			_a PMID: 24462789
504			_aContiene 20 referencias
520			_aObjectives: A growing incidence of pediatric IBD (PIBD) in southern Europe has been recently reported. The SPIRIT registry (1996-2009) confirmed these tendencies in Spain. Our aim is to obtain data from 1985 to 1995 and describe the complete picture of PIBD presentation changes in Spain in the last 25years. Methods: A retrospective survey of incident PIBD in the period 1985-1995 was performed. Patients' data were obtained from the hospitals' databases and compared with the published data from the 1996 to 2009 period. Seventy-eight IBD reference centers took part in this survey. Results: Data from 495 patients were obtained: 278 CD (56.2%), 198 UC (40%), and 19 IBDU (3.8%); 51.7% were female, with higher predominance both in UC (58.6%) and in IBDU (57.9%), but not in CD (46.4%). Median (IQR) age at diagnosis was 12.9 (10.0-15.7) years, with significant differences among IBD subtypes: CD: 13.1 (10.8-16.0) vs UC: 12.4 (9.4-15.1) vs IBDU: 7.5 (3.0-13.0) (p≤0.001). These results are significantly different to the ones in the SPIRIT registry, with a higher proportion of IBDU, younger age and male predominance. The data from both periods taken together give a complete picture of a 25-year period. An annual increase of incident patients was observed, with a ten-fold increase over this period. Conclusion: These data extend the epidemiological trends to a full 25-year period (1985-2009). PIBD incidence in Spain has experienced a sixteen-fold increase. The IBD subtype, localization of the affected segment, age- and sex distribution observed are in accordance with our previously published ones of 1996-2009.
710			_9446 _aServicio de Pediatría-Neonatología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc16636.pdf _ySolicitar documento
942			_2ddc _cART _n0