000 nab a22 7a 4500
999 _c16679
_d16679
003 PC16679
005 20211201111229.0
008 211201b xxu||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _9876
_aAguado García, José María
_eEnfermedades Infecciosas
100 _91210
_aGarcía Reyne, Ana
_eMedicina Interna
245 0 0 _aTuberculosis in solid-organ transplant recipients: disease characteristics and outcomes in the current era.
_h[artículo]
260 _bProgress in transplantation (Aliso Viejo, Calif.),
_c2014
300 _a24(1):37-43.
500 _aFormato Vancouver: Sun HY, Muñoz P, Torre Cisneros J, Aguado JM, Lattes R, Montejo M et al. Tuberculosis in solid-organ transplant recipients: disease characteristics and outcomes in the current era. Prog Transplant. 2014 Mar;24(1):37-43.
501 _aPMID: 24598564
504 _aContiene 14 referencias
520 _aWe determined the characteristics of posttransplant tuberculosis and the impact of rifampin-based antituberculosis regimens on outcomes in the current era. Patients comprised 64 transplant recipients with tuberculosis, divided into 2 consecutive cohorts: an earlier cohort (cases occurring from 2003 to 2007) and a later cohort (cases from 2008 to 2011). Patients from the later versus earlier era had tuberculosis develop later after transplant (odds ratio, 1.01; 95% CI, 1.00-1.02; P= .05), were more likely to be liver transplant recipients (odds ratio, 4.52; 95% CI, 1.32-15.53; P= .02), and were more likely to receive tacrolimus-based immunosuppression (odds ratio, 3.24; 95% CI, 1.14-9.19; P= .03). Mortality rate was 10% in the later cohort and 21% in the earlier cohort (P= .20). Rifampin-based treatment was less likely to be used in patients with prior rejection (P= .04). However, neither rejection rate (P= .71) nor mortality (P= .93) after tuberculosis differed between recipients who received rifampin and recipients who did not. Thus, notable changes have occurred in the epidemiological characteristics of tuberculosis in transplant recipients. Overall mortality rate has improved, with about 90% of the patients now surviving after tuberculosis.
710 _96
_aServicio de Medicina Interna
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc16679.pdf
_ySolicitar documento
942 _2ddc
_cART
_n0