000			02227na a2200241 4500
999			_c1692 _d1692
003			PC1692
005			20191112111022.0
008			130622s2013 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_aBarcena García, Carmen _92081 _eAnatomía Patológica
100			_aMartínez González, Miguel Ángel _91220 _eAnatomía Patológica
100			_aMorales Cerdán, José María _9576 _eNefrología
100			_aRodríguez Gil, Yolanda _9855 _eAnatomía Patológica
245	0	0	_aMembranous glomerulopathy in renal allograft: an ultrastructural study of 17 cases. _h[artículo]
260			_bUltrastructural pathology, _c2013
300			_a37(6):379-85.
500			_aFormato Vancouver: Martínez MA, Bárcena C, Ramchandani B, Rodriguez Gil Y, Morales JM. Membranous glomerulopathy in renal allograft: an ultrastructural study of 17 cases. Ultrastruct Pathol. 2013 Dec;37(6):379-85.
501			_aPMID: 23875894
504			_aContiene 49 referencias
520			_aMembranous glomerulopathy is a common complication of renal allograft. However, its incidence and prognosis are not well defined, because an undetermined number of them pass undiagnosed under the generic epigraph of chronic allograft nephropathy. Materials and methods: To assess the diagnostic refinement supplied by electron microscopy to conventional light and immunofluorescence procedures the authors reviewed 17 cases of electron microscopy-confirmed membranous glomerulonephritis in kidney allograft. In addition, they searched for other features of graft injury, particularly lesions associated with alloimmune reaction, in order to evaluate the contribution of each lesion to the long-term outcome of the allograft. Results: In 4 of the 17 cases of their series the diagnosis of membranous glomerulopathy was made by electron microscopy. In addition, in 5 samples, lesions of chronic alloimmune rejection were present (in 4 cases the diagnosis was based on electron microscopy findings). At the end point of the study, 3 of the 5 patients with chronic alloimmune injury were in dialysis, 1 had died with functioning allograft, and the fifth suffered severe renal failure but was not in dialysis. On the other hand, 3 of the 12 patients without evidence of alloimmune injury had returned to the dialysis program. Conclusions: Electron microscopy is a useful tool in the assessment of renal allograft pathology and can provide additional morphological features of prognostic relevance.
710			_9330 _aServicio de Anatomía Patológica
710			_986 _aServicio de Nefrología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc1692.pdf _ySolicitar documento
942			_n0 _2ddc _cART