000			nab a22 7a 4500
999			_c17103 _d17103
003			PC17103
005			20221129115341.0
008			221129b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_9162 _aLópez Medrano, Francisco _eEnfermedades Infecciosas
245	0	0	_aInfluenza vaccination during the first 6 months after solid organ transplantation is efficacious and safe. _h[artículo]
260			_bClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, _c2015
300			_a21(11):1040.e11-8.
500			_aFormato Vancouver: Pérez Romero P, Bulnes Ramos A, Torre Cisneros J, Gavaldá J, Aydillo TA, Moreno A et al; Influenza Vaccine in Solid Organ Transplant Recipient Study Group, Spanish Network of Research in Infectious Diseases (REIPI-GESITRA); Influenza Vaccine in Solid Organ Transplant Recipient Study Group Spanish Network of Research in Infectious Diseases REIPI-GESITRA. Influenza vaccination during the first 6 months after solid organ transplantation is efficacious and safe. Clin Microbiol Infect. 2015 Nov;21(11):1040.e11-8.
501			_aPMID: 26232537
504			_aContiene 30 referencias
520			_aPreventing influenza infection early after transplantation is essential, given the disease's high mortality. A multicentre prospective cohort study in adult solid organ transplant recipients (SOTR) receiving the influenza vaccine during four consecutive influenza seasons (2009-2013) was performed to assess the immunogenicity and safety of influenza vaccination in SOTR before and 6 months after transplantation. A total of 798 SOTR, 130 of them vaccinated within 6 months of transplantation and 668 of them vaccinated more than 6 months since transplantation. Seroprotection was similar in both groups: 73.1% vs. 76.5% for A/(H1N1)pdm (p 0.49), 67.5% vs. 74.1% for A/H3N2 (p 0.17) and 84.2% vs. 85.2% for influenza B (p 0.80), respectively. Geometric mean titres after vaccination did not differ among groups: 117.32 (95% confidence interval (CI) 81.52, 168.83) vs. 87.43 (95% CI 72.87, 104.91) for A/(H1N1)pdm, 120.45 (95% CI 82.17, 176.57) vs. 97.86 (95% CI 81.34, 117.44) for A/H3N2 and 143.32 (95% CI 103.46, 198.53) vs. 145.54 (95% CI 122.35, 174.24) for influenza B, respectively. After adjusting for confounding factors, time since transplantation was not associated with response to vaccination. No cases of rejection or severe adverse events were detected in patients vaccinated within the first 6 months after transplantation. In conclusion, influenza vaccination within the first 6 months after transplantation is as safe and immunogenic as vaccination thereafter. Thus, administration of the influenza vaccine can be recommended as soon as 1 month after transplantation.
710			_96 _aServicio de Medicina Interna
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17103.pdf _ySolicitar documento
942			_2ddc _cART _n0