000			nab a22 7a 4500
999			_c17106 _d17106
003			PC17106
005			20221129134656.0
008			221129b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_93117 _aOchoa Parra, Nuria _eCardiología
100			_93118 _aNavas Tejedor, Paula _eCardiología
100			_93119 _aMorán Fernández, Laura _eCardiología
100			_91237 _aGómez Sánchez, Miguel Ángel _eCardiología
245	0	0	_aInoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. _h[caso clínico]
260			_bRevista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, _c2015
300			_a34(12):777.e1-5.
500			_aFormato Vancouver: Ortiz Bautista C, Ochoa Parra N, Navas Tejedor P, Morán Fernández L, Gómez Sánchez MÁ. Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. Rev Port Cardiol. 2015 Dec;34(12):777.e1-5.
501			_aPMID: 26632111
504			_aContiene 9 referencias
520			_aA 51-year-old woman presented with a one-year history of progressive dyspnea, WHO functional class III-IV and exercise-related syncope. Transthoracic echocardiography and computed tomography pulmonary angiography were performed, leading to a diagnosis of pulmonary arterial hypertension. She was referred to our pulmonary hypertension unit, where a complete study was performed, including ventilation/perfusion scan, which was consistent with chronic thromboembolic pulmonary hypertension. Risk factors for this condition were excluded and therapeutic options were evaluated. Imaging studies showed distal pulmonary disease so pulmonary endarterectomy was rejected. Further therapeutic options were evaluated and the patient was subsequently enrolled in an open-label uncontrolled trial with riociguat. After one year of treatment, significant improvement in functional class, 6-minute walk test and NT-proBNP were seen, without significant secondary effects.
710			_9119 _aServicio de Cardiología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17106.pdf _ySolicitar documento
942			_2ddc _cCAS _n0