000			nab a22 7a 4500
999			_c17341 _d17341
003			PC17341
005			20230328131235.0
008			230328b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_9238 _aJurado Román, Alfonso _eCardiología
100			_91233 _aHernández Hernández, Felipe _eCardiología
100			_9165 _aGarcía Tejada, Julio _eCardiología
100			_9237 _aGranda Nistal, Carolina _eCardiología
100			_92447 _aMolina Martín de Nicolás, Javier _eCardiología
100			_91241 _aVelázquez Martín, María Teresa _eCardiología
100			_91240 _aAlbarrán González-Trevilla, Agustín _eCardiología
100			_91239 _aTascón Pérez, Juan Carlos _eCardiología
245	0	0	_aRole of hydration in contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention. _h[artículo]
260			_bThe American journal of cardiology, _c2015
300			_a115(9):1174-8.
500			_aFormato Vancouver: Jurado Román A, Hernández Hernández F, García Tejada J, Granda Nistal C, Molina J, Velázquez M et al. Role of hydration in contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention. Am J Cardiol. 2015 May 1;115(9):1174-8.
501			_aPMID: 25759106
504			_aContiene 19 referencias
520			_aTo investigate the role of hydration to prevent contrast-induced nephropathy (CIN) in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PPCI), we prospectively included 408 consecutive patients who were randomly assigned to receive either hydration with isotonic saline (1 ml/kg/h since the beginning of the procedure and for 24 hours after it: NS+ group) or not (NS- group). All patients received an iso-osmolar nonionic contrast medium. The primary end point was the development of CIN: ≥25% or ≥0.5 mg/dl increase in serum creatinine within 3 days after the procedure. CIN was observed in 14% of patients: 21% in the NS- group and 11% in the NS+ group (p=0.016). CIN was significantly associated with death (15.2% vs 2.8%; p<0.0001) and need for dialysis (13.4% vs 0%; p<0.0001). In multivariate analysis, the only predictors of CIN were hydration (OR=0.29 [0.14 to 0.66]; p=0.003) and the hemoglobin before the procedure (OR=0.69 [0.59 to 0.88]; p<0.0001). In conclusion, intravenous saline hydration during PPCI reduced the risk of CIN to 48%. Patients with CIN had increased mortality and need for dialysis. Given the higher incidence of CIN in emergent procedures, and its morbidity and mortality, preventive hydration should be mandatory in them unless contraindicated.
710			_9119 _aServicio de Cardiología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17341.pdf _ySolicitar documento
942			_2ddc _cART _n0