000 nab a22 7a 4500
999 _c17365
_d17365
003 PC17365
005 20230404134252.0
008 230404b xxu||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _92225
_aFontenla Cerezuela, Adolfo
_eCardiología
245 0 0 _aShock Reduction With Multiple Bursts of Antitachycardia Pacing Therapies to Treat Fast Ventricular Tachyarrhythmias in Patients With Implantable Cardioverter Defibrillators: A Multicenter Study.
_h[artículo]
260 _bJournal of cardiovascular electrophysiology,
_c2015
300 _a26(7):774-82.
500 _aFormato Vancouver: Anguera I, Dallaglio P, Martínez Ferrer J, Rodríguez A, Alzueta J, Pérez Villacastín J et al. Shock Reduction With Multiple Bursts of Antitachycardia Pacing Therapies to Treat Fast Ventricular Tachyarrhythmias in Patients With Implantable Cardioverter Defibrillators: A Multicenter Study. J Cardiovasc Electrophysiol. 2015 Jul;26(7):774-82.
501 _aPMID: 25916814
504 _aContiene 29 referencias
520 _aIntroduction: An empirical sequence of burst antitachycardia pacing (ATP) is effective in terminating fast ventricular tachycardias (FVT) in patients with implantable cardioverter-defibrillators (ICDs). We aimed to determine whether multiple ATP bursts for termination of FVT results in shock reduction compared to a single ATP burst. Methods and results: We analyzed data from the Umbrella trial, a multicenter prospective observational study of ICD patients followed by the CareLink Monitoring System. We compared the safety and effectiveness of a single ATP burst (Group 1) with a strategy of successive ATP sequences (Group 2) for termination of FVT episodes (cycle lengths 250-320 milliseconds) before shock therapy. Over a mean follow-up of 35 months, a total of 650 FVT episodes were detected in 154 patients (mean cycle length: 299 ± 18 milliseconds). Effectiveness of the first burst ATP in Group 1 was 73% and shocks were required in 27% of episodes. Effectiveness of the first burst ATP in Group 2 was 77%, and this increased to 91% with the third or successive ATP bursts. Shocks were required in 9% of episodes in group 2, representing a 67% reduction in the need of high-energy shocks. Median duration of FVT episodes and mortality in both groups were similar. Multivariate analysis indicated that programming multiple ATP bursts (OR 3.4, 95%CI 1.7-6.8, P = 0.001) was an independent predictor of ATP effectiveness. Conclusion: This study provides first evidence that a strategy of multiple burst ATP sequences for termination of FVT episodes leads to a clinically meaningful reduction in the need for shocks.
710 _9119
_aServicio de Cardiología
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17365.pdf
_ySolicitar documento
942 _2ddc
_cART
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