000			nab a22 7a 4500
999			_c17383 _d17383
003			PC17383
005			20230414102721.0
008			230414b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_92088 _aMarín Mayor, Marta _ePsiquiatría
100			_9727 _aPonce Alfaro, Guillermo _ePsiquiatría
100			_93245 _aKoeneke, Alejandra _ePsiquiatría
100			_91870 _aMartínez Gras, María Isabel _ePsiquiatría
100			_9656 _aJiménez Arriero, Miguel Ángel _ePsiquiatría
100			_9726 _aRubio Valladolid, Gabriel _ePsiquiatría
245	0	0	_aStartle-response based tasks and laboratory measures of impulsivity in abstinent alcoholic patients. _h[artículo]
260			_bAlcohol and alcoholism : international journal of the Medical Council on Alcoholism, _c2015
300			_a50(3):286-95.
500			_aFormato Vancouver: Marín M, Jurado R, Ponce G, Koeneke A, Martinez-Gras I, Jiménez Arriero MÁ et al. Startle-response based tasks and laboratory measures of impulsivity in abstinent alcoholic patients. Alcohol Alcohol. 2015 May;50(3):286-95.
501			_aPMID: 25737107
504			_aContiene 105 referencias
520			_aAims: It is well known that impulsivity is a risk factor for the development of Addictive Disorders, and more specifically Alcohol Use Disorders (AUD). Recently, the Startle-Response Based Tasks (SRBT) and its different forms of plasticity have been found to be impaired in the alcoholic population. This is the first study to explore the correlation between impulsivity laboratory tasks and the SRBT test, in order to determine whether impulsivity and startle response (SR) could be related and in turn, explain their association with Alcohol Dependence (AD). Subjects: 40 men, who met DSM-IV criteria for AD and had been abstinent for at least one month. Impulsivity was assessed using three laboratory tests: Continuous Performance Test (CPT), Stop-Signal Task (SST) and Differential Reinforcement for Low-Rate Responding (DRL6). Patients also underwent the SR test. They were compared to 40 matched controls. Results: Impulsivity laboratory measures tasks (SST and commissions of the CPT) correlated positively with the magnitude of SR (P < 0.05) and with habituation (P < 0.05). Scores on DRL6 correlated negatively with the magnitude of SR (P < 0.05). This was not found in the control group. Conclusions: The fact that impulsivity laboratory measures and the SR are correlated in patients but not in controls, could imply the existence of a common link for these two measures in alcoholic patients. Our findings support the hypothesis of the existence of two different vulnerability pathways for the development of AUD: anxiety and disinhibitory behaviour.
710			_9150 _aServicio de Psiquiatría
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17383.pdf _ySolicitar documento
942			_2ddc _cART _n0