000			nab a22 7a 4500
999			_c17393 _d17393
003			PC17393
005			20230417130344.0
008			230417b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_93249 _aGómez Cerezo, N _eInstituto de Investigación imas12
100			_93054 _aIzquierdo Barba, Isabel _eInstituto de Investigación imas12
100			_92843 _aArcos, Daniel _eInstituto de Investigación imas12
100			_92644 _aVallet Regí, María _eInstituto de Investigación imas12
245	0	0	_aTailoring the biological response of mesoporous bioactive materials. _h[artículo]
260			_bJournal of materials chemistry. B, _c2015
300			_a3(18):3810-3819.
500			_aFormato Vancouver: Gómez Cerezo N , Izquierdo Barba I , Arcos D , Vallet Regí M . Tailoring the biological response of mesoporous bioactive materials. J Mater Chem B. 2015 May 14;3(18):3810-3819.
501			_aPMID: 32262855
504			_aContiene 54 referencias
520			_aMesoporous bioactive glasses (MBGs) in the SiO2-CaO-P2O5 system have been prepared using different non-ionic structure directing agents (SDA): Brij58, F68, P123 and F127. For the first time, the bioactive response of MBGs can be tailored with the kind of SDA incorporated. This is because, in addition to the textural properties, we can use the SDA to tailor the local atomic environment within the MBG struts. These features lead to differences in the in vitro bioactive behaviour of MBGs. Among the different SDAs used in this work, the triblock copolymer F68 leads to MBGs that exhibit the fastest bioactivity and the fastest differentiation induction from a pre-osteoblast to an osteoblast phenotype. These results are explained in terms of a highly ordered mesoporous structure, more free calcium cations acting as silica network modifiers and small mesopores that avoid the formation of CaP nuclei within pores, which could obstruct the ionic exchange with the surrounding fluids.
710			_9625 _aInstituto de Investigación imas12
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17393.pdf _ySolicitar documento
942			_2ddc _cART _n0