000			nab a22 7a 4500
999			_c17411 _d17411
003			PC17411
005			20230420114648.0
008			230420b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_93254 _aLarach Del Castillo, Jaime _eObstetricia y Ginecología
100			_93255 _aBousamra, Maroun _eObstetricia y Ginecología
100			_93256 _aDe la Fuente, Laura _eObstetricia y Ginecología
100			_93257 _aRuiz Balda, José A. _eObstetricia y Ginecología
100			_93258 _bPalomo, Marissa _eObstetricia y Ginecología
245	0	4	_aThe Impact of Serum Progesterone Levels on the Results of In Vitro Fertilization Treatments: A Literature Review. _h[revisión]
260			_bJBRA assisted reproduction, _c2015
300			_a19(3):141-7.
500			_aFormato Vancouver: Del Castillo JL, Bousamra M, Fuente Lde L, Ruiz Balda JA, Palomo M. The Impact of Serum Progesterone Levels on the Results of In Vitro Fertilization Treatments: A Literature Review. JBRA Assist Reprod. 2015 Aug 1;19(3):141-7.
501			_aPMID: 27203093
504			_aContiene 58 referencias
520			_aThe aim of this review is to analyze the relationship between preovulatory progesterone (P) rise and in vitro fertilization (IVF) pregnancy outcomes. It also investigates the sources and effects of rises in progesterone levels, including the underlying mechanisms and potential strategies in preventing its elevation during ovarian stimulation. Progesterone is produced in the early follicular phase in the adrenal gland, which shifts toward the ovaries prior to ovulation. Several factors contribute to the etiology of P level increase including the number of multiple follicles, the overdose of gonadotropins and poor ovarian response. Nowadays, the influence of the preovulatory P rise on IVF outcome remains controversial. Several authors have failed to demonstrate any negative impact, while others reported a detrimental effect associated with the rise of P. It seems that P rise (1.5 ng/ml or 4.77 nmol/l) may have deleterious effects on endometrial receptivity, namely, accelerating the endometrial maturation process that subsequently narrows the period for implantation and thus decreases pregnancy rates. Recent studies have proposed different cutoffs according to the ovarian response, which may be a little high in patients with high response in relation to those of normal response or low response. To prevent a P rise, it might be preferable to use milder stimulation protocols, earlier trigger of ovulation, cryopreservation of all embryos and transfer in the natural cycle.
710			_9427 _aServicio de Obstetricia y Ginecología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17411.pdf _ySolicitar documento
942			_2ddc _cREV _n0