000 nab a22 7a 4500
999 _c17453
_d17453
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008 230517b xxu||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _91363
_aVilá y Rico, Jesús
_eCirugía Ortopédica y Traumatología
245 0 0 _aTreatment of Osteochondral Lesions of the Talus With Bone Marrow Stimulation and Chitosan-Glycerol Phosphate/Blood Implants (BST-CarGel).
_h[artículo]
260 _bArthroscopy techniques,
_c2015
300 _a4(6):e663-7.
500 _aFormato Vancouver: Vilá Y Rico J, Dalmau A, Chaqués FJ, Asunción J. Treatment of Osteochondral Lesions of the Talus With Bone Marrow Stimulation and Chitosan-Glycerol Phosphate/Blood Implants (BST-CarGel). Arthrosc Tech. 2015 Nov 9;4(6):e663-7.
501 _aPMID: 26870643 PMC4738290
504 _aContiene 10 referencias
520 _aBone marrow stimulation (BMS) techniques represent the first-line treatment for unstable osteochondral lesions of the talus or after conservative treatment failure. These techniques are intended to penetrate the subchondral bone to elicit bleeding and allow precursor cells and cytokines from bone marrow to populate the lesion. However, the fibrocartilaginous repair tissue arising after marrow stimulation confers inferior mechanical and biological properties compared with the original hyaline cartilage. The limitations of BMS can be overcome by the use of the soluble chitosan-based polymer BST-CarGel (Piramal Life Sciences, Laval, Quebec, Canada). When mixed with freshly drawn autologous whole blood and applied to a lesion surgically prepared by BMS, BST-CarGel acts as a natural bioscaffold that increases the quantity and improves the residency of the blood clot formed in the cartilage lesion, enhancing the local healing response. The use of BST-CarGel has been previously described in the knee and hip joints with successful results. We describe the arthroscopic technique for BST-CarGel application in combination with BMS techniques for the treatment of osteochondral lesions of the talus.
710 _9371
_aServicio de Cirugía Ortopédica y Traumatología
856 _uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738290/
_yAcceso libre
942 _2ddc
_cART
_n0