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_c17453 _d17453 |
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040 | _cH12O | ||
041 | _aeng | ||
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_91363 _aVilá y Rico, Jesús _eCirugía Ortopédica y Traumatología |
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245 | 0 | 0 |
_aTreatment of Osteochondral Lesions of the Talus With Bone Marrow Stimulation and Chitosan-Glycerol Phosphate/Blood Implants (BST-CarGel). _h[artículo] |
260 |
_bArthroscopy techniques, _c2015 |
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300 | _a4(6):e663-7. | ||
500 | _aFormato Vancouver: Vilá Y Rico J, Dalmau A, Chaqués FJ, Asunción J. Treatment of Osteochondral Lesions of the Talus With Bone Marrow Stimulation and Chitosan-Glycerol Phosphate/Blood Implants (BST-CarGel). Arthrosc Tech. 2015 Nov 9;4(6):e663-7. | ||
501 | _aPMID: 26870643 PMC4738290 | ||
504 | _aContiene 10 referencias | ||
520 | _aBone marrow stimulation (BMS) techniques represent the first-line treatment for unstable osteochondral lesions of the talus or after conservative treatment failure. These techniques are intended to penetrate the subchondral bone to elicit bleeding and allow precursor cells and cytokines from bone marrow to populate the lesion. However, the fibrocartilaginous repair tissue arising after marrow stimulation confers inferior mechanical and biological properties compared with the original hyaline cartilage. The limitations of BMS can be overcome by the use of the soluble chitosan-based polymer BST-CarGel (Piramal Life Sciences, Laval, Quebec, Canada). When mixed with freshly drawn autologous whole blood and applied to a lesion surgically prepared by BMS, BST-CarGel acts as a natural bioscaffold that increases the quantity and improves the residency of the blood clot formed in the cartilage lesion, enhancing the local healing response. The use of BST-CarGel has been previously described in the knee and hip joints with successful results. We describe the arthroscopic technique for BST-CarGel application in combination with BMS techniques for the treatment of osteochondral lesions of the talus. | ||
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_9371 _aServicio de Cirugía Ortopédica y Traumatología |
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_uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738290/ _yAcceso libre |
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_2ddc _cART _n0 |