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008 230619b xxu||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _91930
_aRomero Otero, Javier
_eUrología
100 _92125
_aGarcía Gómez, Borja
_eUrología
100 _91980
_aDuarte Ojeda, José Manuel
_eUrología
100 _91692
_aRodríguez Antolín, Alfredo
_eUrología
245 0 0 _aActive surveillance for prostate cancer.
_h[revisión]
260 _bInternational journal of urology : official journal of the Japanese Urological Association,
_c2016
300 _a23(3):211-8.
500 _aFormato Vancouver: Romero Otero J, García Gómez B, Duarte Ojeda JM, Rodríguez Antolín A, Vilaseca A, Carlsson SV et al. Active surveillance for prostate cancer. Int J Urol. 2016 Mar;23(3):211-8.
501 _aPMID: 26621054 PMC4966658
504 _aContiene 71 referencias
520 _aIt is worth distinguishing between the two strategies of expectant management for prostate cancer. Watchful waiting entails administering non-curative androgen deprivation therapy to patients on development of symptomatic progression, whereas active surveillance entails delivering curative treatment on signs of disease progression. The objectives of the two management strategies and the patients enrolled in either are different: (i) to review the role of active surveillance as a management strategy for patients with low-risk prostate cancer; and (ii) review the benefits and pitfalls of active surveillance. We carried out a systematic review of active surveillance for prostate cancer in the literature using the National Center for Biotechnology Information's electronic database, PubMed. We carried out a search in English using the terms: active surveillance, prostate cancer, watchful waiting and conservative management. Selected studies were required to have a comprehensive description of the demographic and disease characteristics of the patients at the time of diagnosis, inclusion criteria for surveillance, and a protocol for the patients' follow up. Review articles were included, but not multiple papers from the same datasets. Active surveillance appears to reduce overtreatment in patients with low-risk prostate cancer without compromising cancer-specific survival at 10 years. Therefore, active surveillance is an option for select patients who want to avoid the side-effects inherent to the different types of immediate treatment. However, inclusion criteria for active surveillance and the most appropriate method of monitoring patients on active surveillance have not yet been standardized.
710 _9220
_aServicio de Urología
856 _uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966658/pdf/nihms-764091.pdf
_yAcceso libre
942 _2ddc
_cREV
_n0