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999			_c17735 _d17735
003			PC17735
005			20231106122149.0
008			231106b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_93321 _aCalero García, María Rosa _eRadiodiagnóstico
245	0	0	_aDiagnostic procedures for non-small-cell lung cancer (NSCLC): recommendations of the European Expert Group. _h[revisión]
260			_bThorax, _c2016
300			_a71(2):177-84.
500			_aFormato Vancouver: Dietel M, Bubendorf L, Dingemans AM, Dooms C, Elmberger G, García RC et al. Diagnostic procedures for non-small-cell lung cancer (NSCLC): recommendations of the European Expert Group. Thorax. 2016 Feb;71(2):177-84.
501			_aPMID: 26530085 PMC4752623
504			_aContiene 49 referencias
520			_aBackground: There is currently no Europe-wide consensus on the appropriate preanalytical measures and workflow to optimise procedures for tissue-based molecular testing of non-small-cell lung cancer (NSCLC). To address this, a group of lung cancer experts (see list of authors) convened to discuss and propose standard operating procedures (SOPs) for NSCLC. Methods: Based on earlier meetings and scientific expertise on lung cancer, a multidisciplinary group meeting was aligned. The aim was to include all relevant aspects concerning NSCLC diagnosis. After careful consideration, the following topics were selected and each was reviewed by the experts: surgical resection and sampling; biopsy procedures for analysis; preanalytical and other variables affecting quality of tissue; tissue conservation; testing procedures for epidermal growth factor receptor, anaplastic lymphoma kinase and ROS proto-oncogene 1, receptor tyrosine kinase (ROS1) in lung tissue and cytological specimens; as well as standardised reporting and quality control (QC). Finally, an optimal workflow was described. Results: Suggested optimal procedures and workflows are discussed in detail. The broad consensus was that the complex workflow presented can only be executed effectively by an interdisciplinary approach using a well-trained team. Conclusions: To optimise diagnosis and treatment of patients with NSCLC, it is essential to establish SOPs that are adaptable to the local situation. In addition, a continuous QC system and a local multidisciplinary tumour-type-oriented board are essential.
710			_9462 _aServicio de Radiodiagnóstico
856			_uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752623/pdf/thoraxjnl-2014-206677.pdf _yAcceso libre
942			_2ddc _cREV _n0