000			nab a22 7a 4500
999			_c17740 _d17740
003			PC17740
005			20231107102018.0
008			231107b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_93373 _aMedin, Gabriela _ePediatría
100			_92930 _aGarcía Navarro, Cristina _ePediatría
100			_9443 _aRojo Conejo, Pablo _ePediatría
100			_91354 _aGonzález Tomé, María Isabel _ePediatría
245	0	0	_aDisease disclosure, treatment adherence, and behavioural profile in a cohort of vertically acquired HIV-infected adolescents. _h[artículo]
260			_bAIDS care, _c2016
300			_a28(1):124-30.
500			_aFormato Vancouver: Medin G, García Navarro C, Navarro Gómez M, Ramos Amador JT, Mellado MJ, Jiménez S et al. Disease disclosure, treatment adherence, and behavioural profile in a cohort of vertically acquired HIV-infected adolescents. NeuroCoRISpeS study. AIDS Care. 2016;28(1):124-30.
501			_aPMID: 26307530
504			_aContiene 37 referencias
520			_aAdvances in care and antiretroviral treatment, improved life expectancy and quality of life in children with perinatally-acquired human immunodeficiency virus (HIV) infection. There is increasing interest in the chronic effects of growing up with HIV. The aim of this study was to assess the psychosocial, emotional and behavioural functioning in a cohort of perinatally-acquired HIV-infected adolescents. Data were obtained through semi-structured interviews and the Strengths and Difficulties Questionnaire (SDQ) for emotional and behavioural disorders screening. Results: A total of 95 patients (58% women) were assessed with a median age of 15 years (11-19.1) and a median age at diagnosis of 1.7 years (0-12.2). The median CD4 count, at the inclusion, was 626 cells/mm(3) (132-998), with 34% (10-52%). Viral load was <50 copies/ml in 72% of patients. Eighty-one per cent knew their diagnosis and optimal adherence was achieved in 53%. Passive coping was reported in 58.4% of the adolescents. Only 7.7% of teenagers had a complete and adequate knowledge of their disease and only 18.2% had shared it with their friends. Six unwanted pregnancies occurred (11% of women). Most of them (90%) attended school but 60% had been held back one or more school years. Overall, SDQ scored a risk of behavioural and emotional problems in 24.5%. The report of behaviours associated with hyperactivity was high in 14.9% of the population and borderline in 18.1%. Adolescents with encephalopathy accounted for 44% of those whose total scores fell in either the abnormal and borderline ranges for emotional difficulties (p = .038). Conclusion: Perinatally-acquired HIV-infected adolescents showed significant psychosocial and behavioural health risks that should bring attention to prevention and health care programmes. An earlier disclosure to children could favour a better psychological adjustment and a better treatment adherence. Future studies are needed to assess the relationship between vertically acquired HIV-infection and hyperactivity.
710			_9446 _aServicio de Pediatría-Neonatología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17740.pdf _ySolicitar documento
942			_2ddc _cART _n0