000			02504na a2200373 4500
999			_c332 _d332
003			PC332
005			20191129131020.0
008			130622s2013 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_aRodríguez Peralto, José Luis _91219 _eAnatomía Patológica
245	0	0	_aSaurian papulosis: A new clinicopathological entity. _h[artículo]
260			_c2013 _bJournal of the American Academy of Dermatology,
300			_a68(2):e17-22.
500			_aFormato Vancouver: Molina-Ruiz AM, del Carmen Fariña M, Carrasco L, Santonja C, Rodríguez-Peralto JL, Torrelo A, et al. Saurian papulosis: a new clinicopathological entity. J Am Acad Dermatol. 2013 Feb;68(2):e17-22.
501			_aPMID: 21982635
504			_aContiene 5 referencias
520			_aEpidermal keratinization disorders comprise a heterogeneous group of skin diseases that share the common feature of abnormal epidermal maturation, often leading to a disturbed stratum corneum. Objective: To describe two cases of an unusual disorder of epidermal keratinization. Methods: The clinical features of two unrelated patients with a long-standing widespread cutaneous eruption are described. Histopathologic examination and immunohistochemical studies were performed on skin biopsy specimens. Results: The eruption was characterized by symmetric erythematous, flat, discrete papules with a polygonal shape and fine scaling. The papules covered most of the skin surface and, in some areas of the trunk, they were arranged along the lines of cleavage, parallel to the ribs. There was no facial, mucosal, nail, or palmoplantar involvement; the teeth and hair were normal. The first patient had a sister with an identical eruption, and a brother of the second patient was said to have similar skin lesions. Histopathology revealed well-demarcated areas of compact eosinophilic orthokeratotic hyperkeratosis overlying a slightly acanthotic epidermis. Lesional skin showed weaker immunoexpression for connexin 43 compared with normal skin. Limitations: Only two patients and one sibling were investigated. Conclusion: We propose the name "saurian papulosis" to describe this newly described clinicopathologic entity.
710			_9330 _aServicio de Anatomía Patológica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/3/pc332.pdf _ySolicitar documento
942			_n0 _2ddc _cART