000			01541na a2200361 4500
999			_c4366 _d4366
003			PC4366
005			20180801141949.0
008			130622s2013 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_aSerna Torroba, Javier de la _91469 _eHematología y Hemoterapia
245	0	0	_aComplex, Not Monosomal, Karyotype Is the Cytogenetic Marker of Poorest Prognosis in Patients With Primary Myelodysplastic Syndrome. _h[artículo]
260			_bJournal of Clinical Oncology, _c2013
300			_a31(7):916-22.
500			_aFormato Vancouver: Valcárcel D, Ademà V, Solé F, Ortega M, Nomdedeu B, Sanz G et al. Complex, not monosomal, karyotype is the cytogenetic marker of poorest prognosis in patients with primary myelodysplastic syndrome. J Clin Oncol. 2013 Mar 1;31(7):916-22.
501			_aPMID: 23319689
504			_aContiene 17 referencias
520			_aPurpose Complex karyotype (CK) is the poorest risk factor in patients with myelodysplastic syndrome (MDS). It has recently been reported that monosomal karyotype (MK) worsens the prognosis of patients with CK. Patients and Methods We analyzed 1,054 adult patients with MDS with an abnormal karyotype from the Spanish Registry of MDS. The aim of the study was to describe the incidence, characteristics, and prognosis of MK; the main end points were overall survival (OS) and leukemia-free survival.
710			_9297 _aServicio de Hematología y Hemoterapia
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/4/pc4366.pdf _ySolicitar documento
942			_n0 _2ddc _cART