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| 003 | H12O | ||
| 005 | 20180417112617.0 | ||
| 008 | 130622s2011 xxx||||| |||| 00| 0 eng d | ||
| 040 | _cH120 | ||
| 041 | _aeng | ||
| 100 |
_aJiménez López, Jesús Salvador _91376 _eObstetricia y Ginecología |
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| 245 | 0 | 0 |
_aHysteroscopic dynamic assessment of the endometrium in patients treated with long-term tamoxifen _h[artículo] |
| 260 |
_bJournal of Minimally Invasive Gynecology, _c2011 |
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| 300 | _a18(3):349-354. | ||
| 500 | _aFormato Vancouver: Pérez Medina T, Salazar FJ, San Frutos L, Ríos M, Jiménez JS, Troyano J, et al. Hysteroscopic dynamic assessment of the endometrium in patients treated with long-term tamoxifen. J Minim Invasive Gynecol. 2011;18(3):349-54. | ||
| 501 | _aPMID: 21411378 | ||
| 504 | _aContiene 18 referencias | ||
| 520 | _aStudy objective: To describe the evolutive endometrial hysteroscopic patterns in patients undergoing long-term tamoxifen treatment. Design: Prospective analysis. Analysis of variance test with post hoc :Bonferroni test and homogeneity test of percentages were used for hypothesis contrast between the groups. Design classification: Canadian task force II-2. Setting: Four Spanish tertiary care hospitals. Patients: A total of 278 patients with breast cancer diagnosed between 2002 and 2004, which completed 5-years adjuvant therapy with tamoxifen. Interventions: Ultrasonography and hysteroscopic explorations were performed before starting the treatment and then at yearly intervals during the 5 years of adjuvant treatment. Measurements and main results: Hysteroscopic endometrial changes were significant throughout the years of treatment. Tamoxifen-exposed endometria present five different patterns: atrophic, cystic, hypervascularized, endometrial polyp, and suspicious of malignancy. Endometrial carcinoma appeared in four patients (1.5%) that bled during the follow-up. Conclusion: Tamoxifen produces five different endometrial patterns that evolve dynamically throughout the 5 years of treatment. | ||
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_9427 _aServicio de Obstetricia y Ginecología |
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_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/6/pc6620.pdf _ySolicitar documento |
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_n0 _2ddc _cART |
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_c6620 _d6620 |
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