000 02253na a2200241 4500
003 H12O
005 20180417112619.0
008 130622s2012 xxx||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _aAndrés Belmonte, Amado
_91321
_eNefrología
100 _9576
_aMorales Cerdán, José María
_eNefrología
245 0 0 _aRenal Transplantation from Donors with a Positive Serology for Hepatitis C
_h[artículo]
260 _bContributions to Nephrology,
_c2012
300 _a176:117-29.
500 _aFormato Vancouver: Domínguez-Gil B, Esforzado N, Andrés A, Campistol JM, Morales JM. Renal transplantation from donors with a positive serology for hepatitis C. Contrib Nephrol. 2012;176:117-29.
501 _aPMID: 22310787
504 _aContiene 37 referencias
520 _aTransplantation of kidneys from donors with a positive serology for hepatitis C virus (HCVD+) remains controversial as made evident by wide variations in practice. Current knowledge derived from unicenter and registry experiences have demonstrated that the use of HCVD+ kidneys in HCV+ recipients seems to be safe in the long-term. This information, summarized in this chapter, has provided the basis for internationally agreed recommendations which limit the use of these kidneys for transplantation in recipients with a positive HCV RNA while on the waiting list and consenting in advance. Avoiding superinfection might require matching donors and recipients based on the involved HCV genotype, an approach limited by obvious time constraints. Because the incidence and prevalence of HCV infection is decreasing and there is a proactive treatment of patients with end-stage renal disease and HCV infection before being included on the waiting list, kidneys from HCVD+ are becoming surplus organs due to the lack of appropriate recipients. The underutilization of these kidneys at a moment of dramatic organ shortage requires organizational measures, including the offer of these kidneys for preemptive transplantation, besides the need of reviewing the evidence driving local criteria.
710 _986
_aServicio de Nefrología
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/6/pc6813.pdf
_ySolicitar documento
942 _n0
_2ddc
_cART
999 _c6813
_d6813