000 | 02341na a2200409 4500 | ||
---|---|---|---|
999 |
_c6881 _d6881 |
||
003 | PC6881 | ||
005 | 20210423142554.0 | ||
008 | 130622s2013 xxx||||| |||| 00| 0 eng d | ||
040 | _cH12O | ||
041 | _aeng | ||
100 |
_9652 _aFranco Ugidos, Alejandro _eAparato Digestivo |
||
245 | 0 | 0 |
_aSecond-line Therapy With Levofloxacin After Failure of Treatment to Eradicate Helicobacter pylori Infection Time Trends in a Spanish Multicenter Study of 1000 Patients. _h[artículo] |
260 |
_bJournal of clinical gastroenterology, _c2013 |
||
300 | _a47(2):130-5. | ||
500 | _aFormato Vancouver: Gisbert JP, Pérez-Aisa A, Bermejo F, Castro-Fernández M, Almela P, Barrio J et al. H. pylori Study Group of the Asociación Española de Gastroenterología (Spanish Gastroenterology Association). Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients. J Clin Gastroenterol. 2013 Feb;47(2):130-5. | ||
501 | _aPMID: 22647827 | ||
504 | _aContiene 47 referencias | ||
520 | _aBackground: Second-line bismuth-containing quadruple therapy is complex and frequently induces adverse effects. A triple rescue regimen containing levofloxacin is a potential alternative; however, resistance to quinolones is rapidly increasing. Aim: To evaluate the efficacy and tolerability of a second-line triple-regimen-containing levofloxacin in patients whose Helicobacter pylori eradication treatment failed and to assess whether the efficacy of the regimen decreases with time. Methods: Design: Prospective multicenter study. Patients: In whom treatment with a regimen comprising a proton-pump inhibitor, clarithromycin, and amoxicillin had failed. Intervention: Levofloxacin (500mg bid), amoxicillin (1 g bid), and omeprazole (20mg bid) for 10 days. Outcome: Eradication was confirmed using the C-13-urea breath test 4 to 8 weeks after therapy. Compliance/tolerance: Compliance was determined through questioning and recovery of empty medication envelopes. Incidence of adverse effects was evaluated by means of a questionnaire. | ||
710 |
_9273 _aServicio de Medicina del Aparato Digestivo |
||
856 |
_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/6/pc6881.pdf _ySolicitar documento |
||
942 |
_n0 _2ddc _cART |