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008 | 130622s2013 xxx||||| |||| 00| 0 eng d | ||
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041 | _aeng | ||
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_92238 _aAzcárate, Isabel G. _eInstituto de Investigación imas12 |
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_91902 _aBautista, José M. _eInstituto de Investigación i+12 |
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_aDíez, Amalia _91901 _eInstituto de Investigación i+12 |
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_aMarín García, Patricia _92240 _eInstituto de Investigación i+12 |
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_aPuyet, Antonio _91900 _eInstituto de Investigación i+12 |
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_aInsights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin. _h[artículo] |
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_bBritish journal of pharmacology, _c2013 |
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300 | _a169(3):645-58. | ||
500 | _aFormato Vancouver: Azcárate IG, Marín-García P, Camacho N, Pérez-Benavente S, Puyet A, Diez A et al. Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin. Br J Pharmacol. 2013 Jun;169(3):645-58. | ||
501 | _aPMID: 23488671 | ||
504 | _aContiene 69 referencias | ||
520 | _aBACKGROUND AND PURPOSE: Blood-stage Plasmodium parasites cause morbidity and mortality from malaria. Parasite resistance to drugs makes development of new chemotherapies an urgency. Aminoacyl-tRNA synthetases have been validated as antimalarial drug targets. We explored long-term effects of borrelidin and mupirocin in lethal P. yoelii murine malaria. | ||
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_9625 _aInstituto de Investigación imas12 |
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_uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682711/ _yAcceso libre |
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_c7366 _d7366 |